Pleo Art A

Arthrokehlan A (Pleo™ Art "A") - for conditions of degenerative diseases of the spinal

column and entire apparatus of locomotion including arthritis, osteoporosis, ankylosing

spondylolysis and dental conditions.

Medicinal ingredient: Propionibacterium acnes DSM 4217

Pleo Art A Arthrokehlan® “A” 6X

Drops

Liquid dilution

for oral intake, rubbing in

Active ingredient: Propionibacterium acnes extract 6X

Composition: 1 ml liquid dilution contains: Medically active substance: 1 ml Propionibacterium

acnes 6X dil. Other constituents: purified water.

Characteristics: Pleo Art A Arthrokehlan “A” is gained through the cultivation of Siphonospora polymorpha

which have been isolated from the bacterial flora of human dental

granuloma. In accordance with Dr. v. Brehmer’s method, a formol toxoid (a

detoxified culture filtrate) is produced from these cultures. It effects a sustained

rise in the defensive capacity.

According to experience, Arthritic, arthrotic, as well as degenerative diseases of the spinal column

to be administered in and the entire apparatus of locomotion, myalgia.

cases of:

Application: Unless otherwise prescribed: For oral intake: 1 x daily 5-10 drops before a

meal.

For rubbing in: 1 x daily 5-10 drops at the location of the disease or

into the bend of the elbow.

Contraindications: In cases of known hypersensitivity to Propionibacterium acnes, as a precaution,

this preparation should not be administered.

Adverse reactions: None known. Because of specific organic components of Pleo Art A Arthrokehlan “A”,

hypersensitivity theoretically may occur. In this case, discontinue medication

and treat symptomatically.

Interactions with other remedies: None known.

Side effects: None known.

Precautions: As with all medications and due to the variations of clinical studies, professional

medical advice should be sought prior to recommending this product

to women during pregnancy or breastfeeding, as well as with children.

Duration of treatment: Dependent on the advice of the physician or health care professional.

Advice: Pleo Art A Arthrokehlan “A” was previously marketed under the names Spezial-

Anatoxin “A” and Arthrisinal.

How supplied: The following dosage forms are available: 10 ml dropper bottle 6X, 1 ml

ampule 10 and 50 6X.

Pleo Art A Arthrokehlan® “A” 6X

Ampules

Liquid dilution for injection

Active ingredient: Propionibacterium acnes extract 6X

Composition: 1 ampule of 1 ml contains:

Medically active substance: 1 ml Propionibacterium

acnes 6X aqueous dilut. Other constituents: isotonic sodium chloride

solution.

Characteristics: Pleo Art A Arthrokehlan “A” is gained through the cultivation of Siphonospora polymorpha

which have been isolated from the bacterial flora of human dental

granuloma. In accordance with Dr. v. Brehmer’s method, a formol toxoid (a

detoxified culture filtrate) is produced from these cultures. It effects a sustained

rise in the defensive capacity.

According to experience, Arthritic, arthrotic, as well as degenerative diseases of the spinal column

to be administered in and the entire apparatus of locomotion, myalgia.

cases of:

Application: Unless otherwise prescribed: 0.2-1.0 ml to be injected deep intramuscularly

- regular intragluteally - at the lying patient, 2-3 x weekly. In case of strong

reactions, injections have to be discontinued; the treatment can be continued

with the dosage form drops. As a general advice the dosage has to be

chosen adequately, so that strong general reactions do not occur and that

the local reactions are confined to the site of injections.

Contraindications: Fever, conditions of weakness. In cases of known hypersensitivity to Propionibacterium

acnes, as a precaution, this preparation should not be administered.

Adverse reactions: None known. Generally well tolerated. Occasionally local reactions like rubefaction,

swelling or painfulness may be observed, normally vanishing without

treatment. These effects are not to be seen as adverse reactions, but

rather as an expression of effectiveness. In the first 2 or 3 days after the

injection sometimes conditions of weakness, fortified expectoration, slight

painfulness of the region or subfebrile temperatures may show. Strong

general reactions are always a sign of overdosage or of incorrect injection

technique.

Interactions None known. An interval of four weeks should be kept to the administration

with other remedies: of vaccinations. In cases of simultaneous treatment with immunosuppressive

remedies, the effectiveness of Pleo Art A Arthrokehlan “A” may be influenced.

Side effects: None known.

Precautions: As with all medications and due to the variations of clinical studies, professional

medical advice should be sought prior to recommending this product

to women during pregnancy or breastfeeding, as well as with children.

Duration of treatment: Dependent on the advice of the physician or health care professional.

Advice: Pleo Art A Arthrokehlan “A” was previously marketed under the names Spezial-

Anatoxin “A” and Arthrisinal.

How supplied: The following dosage forms are available: 10 ml dropper bottle 6X, 1 ml

ampule 10 and 50 6X.